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Magic™ Antibody Discovery - Human Jagged 1 / JAG1 (34-1046) Membrane Protein, Partial, -His tag (CAT#: MP0883F)

Datasheet
This membrane protein is Human Jagged 1 / JAG1 (561-852). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Jagged 1 / JAG1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 112.3 kDa. The protein migrates as 130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 34 - Ser 1046 (Accession # P78504-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Jagged 1 / JAG1
  • Full Name
  • jagged canonical Notch ligand 1
  • Introduction
  • The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
  • Alternative Names
  • AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1; protein jagged-1

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