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Magic™ Antibody Discovery - Human PADI2 (1-665) Membrane Protein, Partial, His- tag (CAT#: MP0809F)

Datasheet
This membrane protein is Human PADI2 (1-665). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PADI2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 77.6 kDa.
  • Sequence
  • AA Met 1 - Pro 665 (Accession # Q9Y2J8-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Buffer
  • Delivered as bulk protein in a 0.2 μm filtered solution of PBS, pH7.4 with glycerol as protectant.

Target

  • Target Protein
  • PADI2
  • Full Name
  • peptidyl arginine deiminase 2
  • Introduction
  • This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
  • Alternative Names
  • PAD2; PDI2; PAD-H19; protein-arginine deiminase type-2; peptidyl arginine deiminase, type II; protein-arginine deiminase type II

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