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Magic™ Antibody Discovery - Human PSCA (12-86) Membrane Protein, Partial, -His tag (CAT#: MP0756F)

Datasheet
This membrane protein is Human PSCA (12-86). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PSCA
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 10.4 kDa. The protein migrates as 18-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 12 - Ser 86 (Accession # O43653-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • PSCA
  • Full Name
  • prostate stem cell antigen
  • Introduction
  • This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • PRO232; prostate stem cell antigen

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