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Magic™ Antibody Discovery - Mouse IL-23 R (24-372) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0228F)

Datasheet
This membrane protein is Mouse IL-23 R (24-372). It has been tested in SDS-PAGE, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • IL-23 R
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 66.8 kDa. As a result of glycosylation, the protein migrates as 90-100 kDa under reducing (R) condition, and 180-200 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Gly 24 - Asp 372 (Accession # NP_653131).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, BLI
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • IL-23 R
  • Full Name
  • interleukin 23 receptor
  • Introduction
  • The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
  • Alternative Names
  • IL-23R, interleukin-23 receptor, IL-23 receptor

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