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Magic™ Membrane Protein Human DRD4 (Dopamine receptor D4) Full Length (CAT#: MPC0082K) Made to Order

This product is a 43.9 kDa Human DRD4 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DRD4
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 43.9 kDa
  • TMD
  • 7
  • Sequence
  • MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLA
    GNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGA
    WLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSR
    RQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCS
    FFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPA
    PRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
    LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPV
    VVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIY
    TVFNAEFRNVFRKALRACC

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • DRD4
  • Full Name
  • Dopamine receptor D4
  • Introduction
  • This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
  • Alternative Names
  • D4DR; D(4) dopamine receptor; D(2C) dopamine receptor; dopamine D4 receptor; seven transmembrane helix receptor; DRD4; Dopamine receptor D4

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