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Magic™ Membrane Protein Human FREM2 (FRAS1 related extracellular matrix 2) Full Length (CAT#: MPC4294K) Made to Order

This product is a made-to-order Human FREM2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FREM2
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • TMD
  • 1
  • Sequence
  • MHSAGTPGLSSRRTGNSTSFQPGPPPPPRLLLLLLLLLSLVSRVPAQPAA
    FGRALLSPGLAGAAGVPAEEAIVLANRGLRVPFGREVWLDPLHDLVLQVQ
    PGDRCAVSVLDNDALAQRPGRLSPKRFPCDFGPGEVRYSHLGARSPSRDR
    VRLQLRYDAPGGAVVLPLVLEVEVVFTQLEVVTRNLPLVVEELLGTSNAL
    DARSLEFAFQPETEECRVGILSGLGALPRYGELLHYPQVPGGAREGGAPE
    TLLMDCKAFQELGVRYRHTAASRSPNRDWIPMVVELRSRGAPVGSPALKR
    EHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTALTPDMLAAEDAES
    PSDLLIFNLTSPFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPPSE
    DSDQERLFELELEVVDLEGAASDPFAFMVVVKPMNTMAPVVTRNTGLILY
    EGQSRPLTGPAGSGPQNLVISDEDDLEAVRLEVVAGLRHGHLVILGASSG
    SSAPKSFTVAELAAGQVVYQHDDRDGSLSDNLVLRMVDGGGRHQVQFLFP
    ITLVPVDDQPPVLNANTGLTLAEGETVPILPLSLSATDMDSDDSLLLFVL
    ESPFLTTGHLLLRQTHPPHEKQELLRGLWRKEGAFYERTVTEWQQQDITE
    GRLFYRHSGPHSPGPVTDQFTFRVQDNHDPPNQSGLQRFVIRIHPVDRLP
    PELGSGCPLRMVVQESQLTPLRKKWLRYTDLDTDDRELRYTVTQSPTDTD
    ENHLPAPLGTLVLTDNPSVVVTHFTQAQINHHKIAYRPPGQELGVATRVA
    QFQFQVEDRAGNVAPGTFTLYLHPVDNQPPEILNTGFTIQEKGHHILSET
    ELHVNDVDTDVAHISFTLTQAPKHGHMRVSGQILHVGGLFHLEDIKQGRV
    SYAHNGDKSLTDSCSLEVSDRHHVVPITLRVNVRPVDDEVPILSHPTGTL
    ESYLDVLENGATEITANVIKGTNEETDDLMLTFLLEDPPLYGEILVNGIP
    AEQFTQRDILEGSVVYTHTSGEIGLLPKADSFNLSLSDMSQEWRIGGNTI
    QGVTIWVTILPVDSQAPEIFVGEQLIVMEGDKSVITSVHISAEDVDSLND
    DILCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFNLKDLRQGHINYVQ
    SVHKGVEPVEDRFVFRCSDGINFSERQFFPIVIIPTNDEQPEMFMREFMV
    MEGMSLVIDTPILNAADADVPLDDLTFTITQFPTHGHIMNQLINGTVLVE
    SFTLDQIIESSSIIYEHDDSETQEDSFVIKLTDGKHSVEKTVLIIVIPVD
    DETPRMTINNGLEIEIGDTKIINNKILMATDLDSEDKSLVYIIRYGPGHG
    LLQRRKPTGAFENITLGMNFTQDEVDRNLIQYVHLGQEGIRDLIKFDVTD
    GINPLIDRYFYVSIGSIDIVFPDVISKGVSLKEGGKVTLTTDLLSTSDLN
    SPDENLVFTITRAPMRGHLECTDQPGVSITSFTQLQLAGNKIYYIHTADD
    EVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHKLVVSESENKL
    ITPFELTVEDRDTPDKLLKFTITQVPIHGHLLFNNTRPVMVFTKQDLNEN
    LISYKHDGTESSEDSFSFTVTDGTHTDFYVFPDTVFETRRPQVMKIQVLA
    VDNSVPQIAVNKGASTLRTLATGHLGFMITSKILKVEDRDSLHISLRFIV
    TEAPQHGYLLNLDKGNHSITQFTQADIDDMKICYVLREGANATSDMFYFA
    VEDGGGNKLTYQNFRLNWAWISFEKEYYLVNEDSKFLDVVLKRRGYLGET
    SFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQS
    ETFQVVLSEPVLAALEFPTVATVEIVDPGDEPTVFIPQSKYSVEEDVGEL
    FIPIRRSGDVSQELMVVCYTQQGTATGTVPTSVLSYSDYISRPEDHTSVV
    RFDKDEREKLCRIVIIDDSLYEEEETFHVLLSMPMGGRIGSEFPGAQVTI
    VPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTDLSKSSSVTVRSRKT
    DPPSADAGTDYVGISRNLDFAPGVNMQPVRVVILDDLGQPALEGIEKFEL
    VLRMPMNAALGEPSKATVSINDSVSDLPKMQFKERIYTGSESDGQIVTMI
    HRTGDVQYRSSVRCYTRQGSAQVMMDFEERPNTDTSIITFLPGETEKPCI
    LELMDDVLYEEVEELRLVLGTPQSNSPFGAAVGEQNETLIRIRDDADKTV
    IKFGETKFSVTEPKEPGESVVIRIPVIRQGDTSKVSIVRVHTKDGSATSG
    EDYHPVSEEIEFKEGETQHVVEIEVTFDGVREMREAFTVHLKPDENMIAE
    MQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDDTSKAKESAEPMSGYP
    VICITACNPKYSDYDKTGSICASENINDTLTRYRWLISAPAGPDGVTSPM
    REVDFDTFFTSSKMVTLDSIYFQPGSRVQCAARAVNTNGDEGLELMSPIV
    TISREEGLCQPRVPGVVGAEPFSAKLRYTGPEDADYTNLIKLTVTMPHID
    GMLPVISTRELSNFELTLSPDGTRVGNHKCSNLLDYTEVKTHYGFLTDAT
    KNPEIIGETYPYQYSLSIRGSTTLRFYRNLNLEACLWEFVSYYDMSELLA
    DCGGTIGTDGQVLNLVQSYVTLRVPLYVSYVFHSPVGVGGWQHFDLKSEL
    RLTFVYDTAILWNDGIGSPPEAELQGSLYPTSMRIGDEGRLAVHFKTEAQ
    FHGLFVLSHPASFTSSVIMSADHPGLTFSLRLIRSEPTYNQPVQQWSFVS
    DFAVRDYSGTYTVKLVPCTAPSHQEYRLPVTCNPREPVTFDLDIRFQQVS
    DPVAAEFSLNTQMYLLSKKSLWLSDGSMGFGQESDVAFAEGDIIYGRVMV
    DPVQNLGDSFYCSIEKVFLCTGADGYVPKYSPMNAEYGCLADSPSLLYRF
    KIVDKAQPETQATSFGNVLFNAKLAVDDPEAILLVNQPGSDGFKVDSTPL
    FQVALGREWYIHTIYTVRSKDNANRGIGKRSVEYHSLVSQGKPQSTTKSR
    KKREIRSTPSLAWEIGAENSRGTNIQHIALDRTKRQIPHGRAPPDGILPW
    ELNSPSSAVSLVTVVGGTTVGLLTICLTVIAVLMCRGKESFRGKDAPKGS
    SSSEPMVPPQSHHNDSSEV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • FREM2
  • Full Name
  • FRAS1 related extracellular matrix 2
  • Introduction
  • This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.
  • Alternative Names
  • FREM2; CRYPTOP; FRASRS2; FRAS1-related extracellular matrix protein 2; ECM3 homolog; FRAS1 related extracellular matrix protein 2; FRAS1 related extracellular matrix 2

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