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Magic™ Membrane Protein Human KCNH1 (Potassium voltage-gated channel subfamily H member 1) Full Length (CAT#: MPC0594K) Made to Order

Datasheet
This product is a 111.4 kDa Human KCNH1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNH1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 111.4 kDa
  • TMD
  • 6
  • Sequence
  • MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFC
    KLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMY
    KKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGK
    FARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQ
    EAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAW
    LVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDL
    LSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLF
    SSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSI
    GDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVY
    ISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTT
    IFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGI
    DTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTV
    HCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWK
    EATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYN
    LRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEA
    RLAAERGGRDLDDLDVEKGNVLTEHASANHSLVKASVVTVRESPATPVSF
    QAASTSGVPDHAKLQAPGSECLGPKGGGGDCAKRKSWARFKDACGKSEDW
    NKVSKAESMETLPERTKASGEATLKKTDSCDSGITKSDLRLDNVGEARSP
    QDRSPILAEVKHSFYPIPEQTLQATVLEVRHELKEDIKALNAKMTNIEKQ
    LSEILRILTSRRSSQSPQELFEISRPQSPESERDIFGAS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNH1
  • Full Name
  • Potassium voltage-gated channel subfamily H member 1
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
  • Alternative Names
  • EAG; EAG1; ZLS1; hEAG; TMBTS; h-eag; hEAG1; Kv10.1; potassium voltage-gated channel subfamily H member 1; EAG channel 1; ether-a-go-go 1; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; potassium channel, voltage gated eag related subfamily H, member 1; potassium voltage-gated channel, subfamily H (eag-related), member 1; voltage-gated potassium channel subunit Kv10.1; KCNH1; Potassium voltage-gated channel subfamily H member 1

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