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Magic™ Membrane Protein Human S1PR1 (Sphingosine-1-phosphate receptor 1) Full Length (CAT#: MPC0348K) Made to Order

This product is a 42.8 kDa Human S1PR1 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • S1PR1
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 42.8 kDa
  • TMD
  • 7
  • Sequence
  • MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSV
    VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTA
    NLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMK
    LHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHK
    HYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEK
    SLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
    VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEF
    SRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag and 10xHis tag at N-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • S1PR1
  • Full Name
  • Sphingosine-1-phosphate receptor 1
  • Introduction
  • The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362; sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; S1PR1; Sphingosine-1-phosphate receptor 1

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