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NativeExtract™ Human HTR4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX344)

Datasheet
This product is recombinant Human HTR4 protein in native nanodisc form. The synthetic compound we developed can solubilize the HTR4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HTR4
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.8kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HTR4
  • Full Name
  • 5-hydroxytryptamine receptor 4
  • Introduction
  • This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described.
  • Alternative Names
  • 5-HT4; 5-HT4R; 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled; 5-hydroxytryptamine receptor 4 transcript variant b2; 5-hydroxytryptamine receptor 4 transcript variant b3; cardiac 5-HT4 receptor; HTR4; 5-hydroxytryptamine receptor 4

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