Bovine Viral Diarrhea Virus Vaccine
Creative Biolabs is a leading global research institute which provides a series of viral vaccine development solutions for worldwide customers. With our proven competencies and regulatory expertise, we are therefore confident in offering the best services for bovine viral diarrhea virus vaccine development and guarantee the finest results for our customers all over the world.
Bovine viral diarrhea virus (BVDV), a member of Flaviviridae family, is a significant cause of a wide variety of cattle clinical syndromes, such as respiratory or enteric diseases, and is also associated with high mortality acute and peracute infections. It is a type of small, enveloped, single-stranded RNA virus that mainly exists in the cattle industry. Generally speaking, BVDV can be divided into two types, BVDV-1, and BVDV-2, based on their ability to induce host cell microscopically visible. Type 1 is subdivided into 16 subtypes (a-p) and type 2 can be grouped into 3 subtypes (a-c). Studies conducted on BVDV show that it plays an important role in protective immunity development.
Fig.1 The Immune Mechanism of Bovine Viral Diarrhea Virus. (Chase C.C, et al., 2015)
The Inactivated Bovine Viral Diarrhea Virus Vaccine
Inactivated BVDV vaccine is the most classic and earliest vaccine for bovine viral diarrhea virus prevention. Up to now, more than 180 USDA licensed BVDV vaccines are widely used around the world. Inactivated BVDV vaccines generally can be divided into two types according to antigenic diversity of BVDV strains. Recent data demonstrate that inactivated BVDV vaccines can be safe and effective on both type 1 and type 2 BVDV infections as well as providing protection against fetal infection. Inactivated vaccines contain unreproducible viral antigens, thereby reducing the risk of adverse effects in vaccinates and developing fetus in pregnant animals.
The Modified-Live Viral BVDV Vaccine
BVDV vaccine studies have been focused on modified-live vaccine development for decades because of its high concentrations of viral neutralizing antibodies and cell-mediated immunity. MLV vaccines can be expected to provide rapid protection after only a single dose of the vaccine. The onset of immunity from MLV vaccines may thus be useful in 3 days with complete protection observed by 5 days following vaccine administration. The MLV vaccine has been widely used in many cattle disease prevention, and the results show it plays an important role in the clinic.
Our Services for Bovine Viral Diarrhea Virus Vaccine
Our platform is strictly in accordance with GCP's requirements, and the temperature, humidity and experimental facilities in the laboratory are all world-advanced. We provide a comprehensive viral vaccines development for bovine viral diarrhea virus vaccine project.
- Well-established viral vaccine development system
- Rapid results, flexible development service
- Multiple robust technologies
Creative Biolabs is a research-driven and customer-focused company, which has focused on the viral vaccine development services for years. If you are interested in our services, please contact us for more details.
Reference
- Chase C.C, et al. (2015). “Immune response to bovine viral diarrhea virus--looking at newly defined targets.” Anim Health Res Rev.16(1), 4-14.
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
