Specific Positioning Antibody Development Services

Creative Biolabs can endow intrabodies with specific cellular destination (ER, Mitochondria, Golgi complex, Nucleus, etc.) and membrane anchoring via particular modifications. In terms of our advanced Super™ intrabody development platform, our scientists can offer a full line of the best intrabody with almost every specific intracellular targeting localization and extracellular space via fusion of versatile signal peptides. With over decades professional experience in antibody engineering field, our scientists can achieve specific positioning antibodies to the desired position properly.

Specific Intracellular Positioning

Regarding decades’ diligent efforts, our scientific knowledge has revealed eukaryotic cells with more sophisticated and functionally distinct membrane compartments for single or multiple particular biological functions. For instance, the nucleus, which contains the most fascinating genetic materials acting like the very original blueprint for every single cell or organism; and the mitochondria, which is the most critical organelle to generate ATP and other minor energy bars for powering all the motion and other bioprocesses. Like the tiniest functional bricks of viable bioprocesses, Creative Biolabs is able to genetically engineered several categories of proteins, especially intrabodies, to achieve specific intracellular membrane anchoring or compartment residences for multiple purposes, such as research requirements or therapeutic needs.

Our scientists are able to engineer intrabodies with the most creative methods for customized anchoring, residences, and novel requirements. A series of specific positioning can be achieved including but not limited to:

Custom Intrabody Discovery and Development

With our decades’ professional experience, Creative Biolabs can offer one-stop Intrabody discovery and development services with our advanced techniques (e.g. IAC technology, bacterial two-hybrid technology, and mammalian two-hybrid technology). Once customer’s desired intrabody is captured and validated with multiple strict tests, we highly recommend further adoption of our specific positioning intrabody development technology to achieve specific intracellular localization of the select intrabodies.

Typical Intrabody Discovery Services

• Intracellular Functional sdAb Development
• IntraMab Development
• Intracellular Functional Scaffold Development

Fig. 1 Intracellular compartments for intrabody’s specific localization

At Creative Biolabs, we are always eager to create evolutional strategy and develop more novel and advanced technology to add wings on our clients’ valuable projects. Our scientists are dedicated to directly overcoming or indirectly bypassing almost every challenging bottleneck in the discovery and development of specific intrabodies. If you are interested in developing novel intrabodies, please do not hesitate to inquire us for more detailed information.

All of our antibody products and services can only be used for preclinical research studies. Do not use them on humans.