Dexamethasone Palmitate Acid Liposome (CAT#: LDLY-1023-LD2)

Description
Dexamethasone palmitate acid is a non-specific carrier anti-inflammatory drug. This product is a pre-formulated liposome with dexamethasone palmitate acid. It is only for research purposes and for the injection to laboratory animals.
Lipid Composition
Cholesterol, DPPC
Encapsulated Drug
Dexamethasone Palmitate Acid
Buffer
PBS, pH 6.5
Storage
Store in dark at +4°C and do not freeze
Size
200 nm
Quantity
5mL (available in lyophilized powder)
Download
DataSheet MSDS
FAQs Customer Reviews Related Sections
  1. What is dexamethasone palmitate acid liposome used for in research?

    This liposomal formulation is primarily used for its potent anti-inflammatory effects in research settings, particularly in studies aimed at investigating inflammatory diseases and their therapeutic management. It provides a targeted delivery system that enhances the bioavailability and efficacy of dexamethasone at inflamed sites while minimizing systemic exposure.

  2. How does dexamethasone palmitate improve the efficacy of dexamethasone?

    Dexamethasone palmitate is a lipophilic ester of dexamethasone that enhances the drug's incorporation into liposomal bilayers, which improves its solubility and stability in biological systems. This modification allows for prolonged release and targeted delivery of the corticosteroid to inflamed tissues, thereby increasing its therapeutic efficacy and reducing side effects.

  3. What are the benefits of using liposomal delivery for dexamethasone palmitate?

    Liposomal encapsulation of dexamethasone palmitate reduces the clearance rate of the drug, extends its circulation time in the bloodstream, and facilitates the accumulation of the drug at sites of inflammation through enhanced permeability and retention (EPR) effect. This targeted delivery helps in achieving higher local drug concentrations at the disease site, which is crucial for effective treatment.

  4. Are there specific diseases or conditions where dexamethasone palmitate acid liposomes are particularly effective?

    These liposomes are particularly effective in treating chronic inflammatory conditions such as rheumatoid arthritis, and are also being explored for their efficacy in treating lung diseases and other inflammatory disorders where targeted corticosteroid therapy is beneficial.

  5. What are the key physical and chemical properties of dexamethasone palmitate acid liposomes?

    Dexamethasone palmitate acid liposomes typically exhibit stability due to their composition, which often includes cholesterol and other phospholipids that help stabilize the liposomal structure. They may vary in size but are usually designed to optimize cellular uptake and drug release kinetics.

  • Advanced Inflammatory Control
    Creative Biolabs' dexamethasone palmitate liposomes have significantly enhanced our research on inflammation control, providing targeted delivery with impressive efficacy.
  • Precision Targeting for Therapy
    These liposomes offer precision targeting, greatly improving the delivery of dexamethasone to inflamed tissues, which is vital for our studies on chronic inflammatory diseases.
  • Creative Biolabs' Breakthrough in Liposomal Delivery
    Creative Biolabs has revolutionized liposomal technology with their dexamethasone palmitate products, ensuring efficient and sustained delivery in our therapeutic models.
  • Enhanced Bioavailability and Effect
    Creative Biolabs' liposomes have markedly improved the bioavailability and therapeutic effect of dexamethasone palmitate, making them indispensable in our pharmacokinetic studies.
  • Optimized Formulation for Research Excellence
    Creative Biolabs' optimized formulation of dexamethasone palmitate liposomes exhibits superior stability and controlled release, essential for our ongoing research applications.

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For Research Use Only. Not For Clinical Use

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