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Magic™ Membrane Protein Human KMO (Kynurenine 3-monooxygenase) Expressed in Baculovirus/Insect expression system for Antibody Discovery, Partial (2-441aa) (CAT#: MPX0513K)

Datasheet
This product is a 51 kDa Human KMO membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KMO
  • Protein Length
  • Partial (2-441aa)
  • Protein Class
  • Oxidoreductase
  • Molecular Weight
  • 51 kDa
  • TMD
  • 1
  • Sequence
  • DSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTR
    GRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYG
    TKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLG
    SDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIP
    PKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTS
    NDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCV
    LLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRI
    PDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTM
    VTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLL

Product Description

  • Activity
  • Yes
  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • 6xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Endotoxin
  • <1.0 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >80%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 μg per lane
  • Buffer
  • Supplied as a 0.2 μm filtered solution in Tris, NaCl and Brij-35.

Target

  • Target Protein
  • KMO
  • Full Name
  • Kynurenine 3-monooxygenase
  • Introduction
  • This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.
  • Alternative Names
  • KMO; dJ317G22.1; kynurenine 3-hydroxylase; Kynurenine 3-monooxygenase

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