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Magic™ Membrane Protein Human LRIG2 (Leucine rich repeats and immunoglobulin like domains 2) Expressed in CHO for Antibody Discovery, Partial (41-805aa) (CAT#: MPX0444K)

Datasheet
This product is a 112 kDa Human LRIG2 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LRIG2
  • Protein Length
  • Partial (41-805aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 112 kDa
  • TMD
  • 1
  • Sequence
  • GLCPAPCSCR
    IPLLDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISLESQTLQ
    EVKMNYNELTEIPYFGEPTSNITLLSLVHNIIPEINAQALQFYPALESLD
    LSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLN
    RNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG
    ISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE
    RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHI
    ADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKS
    ITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSLLCDCH
    LKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQI
    RTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVR
    YWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNE
    MPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERR
    MHVMPEDDVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIR
    PLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL
    LIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSSIGHED
    DGWTT

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • hIgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • LRIG2
  • Full Name
  • Leucine rich repeats and immunoglobulin like domains 2
  • Introduction
  • This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • LRIG2; LIG2; UFS2; LIG-2; leucine-rich repeats and immunoglobulin-like domains protein 2; Leucine rich repeats and immunoglobulin like domains 2

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