Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsThe team at Creative Biolabs specializes in providing cutting-edge Anti-GPCR Antibody Discovery services utilizing advanced Yeast Display Technology. Our platform is designed to efficiently generate and identify high-affinity antibodies that target GPCRs - critical and often challenging targets for drug discovery, given their involvement in a wide range of diseases such as cancer, neurological disorders, cardiovascular diseases, and metabolic conditions.
| Species | Antibody Library ID | Display Technology | Library Format | Library Size |
| VHH (Llama) | LlaVHH-YDP-1 | Yeast Display | Naïve VHH | 1.5×108 |
| Human | HuscL-YDP-3 | Yeast Display | Naïve scFv | 1.9×108 |
We provide a comprehensive range of yeast display library screening services addressing diverse scientific challenges. For more information, please visit the service pages linked below:
Premade Yeast Display SdAb Library Screening
Premade Yeast Display ScFv Library Screening
Yeast Display Immune Antibody Library Screening
Yeast Display Antibody Library Screening for Cell-based Target
Yeast Display Library Screening for Mutant Epitope Specific Antibody
Yeast Display Library Screening for TCR-Like Antibody
Yeast Display Library Screening for pH-Dependent Antibody
To ensure an accurate representation of your GPCR target during antibody screening, it is essential to present the receptor in a membrane-like environment. We provide comprehensive GPCR antigen preparation services, utilizing advanced techniques such as high-expression GPCR cell lines, liposomes, and solid-phase immobilization. These approaches preserve the receptor's natural structure and function, enabling the precise identification of high-affinity antibodies.
We specialize in generating diverse yeast display antibody libraries tailored to your project needs. Our libraries, which can include scFvs, Fabs, VHHs, or whole antibodies, are designed to display a broad range of antibodies, ensuring the identification of binders to your specific GPCR targets.
Antibody screening is performed using flow cytometry to identify yeast cells displaying antibodies that bind specifically to your GPCR target. Our approach enables rapid, high-throughput sorting of yeast cells based on their binding to the GPCR, ensuring the selection of the best antibody candidates. We also provide rigorous quality controls and further affinity maturation, ensuring that the final antibody candidates exhibit the highest possible affinity and specificity.
After selecting high-affinity binders, we clone the corresponding antibody genes into expression vectors and express them for purification. The purified antibodies are then characterized for binding affinity, specificity, and functionality through assays.
GPCRs are membrane-bound proteins that are difficult to express and stabilize in many systems. We could provide suitable a strategy to mimic the membrane environment, ensuring functional and biologically relevant antibodies targeting these challenging receptors.
Yeast display enables screening of large antibody libraries with high efficiency, allowing for rapid identification of specific binders to GPCRs - much faster than traditional methods.
Yeast display supports various antibody formats, including scFvs, Fabs, VHHs, and full antibodies. This flexibility helps generate antibodies with diverse binding and functional properties, tailored to specific experimental needs.
Yeast cells can perform key post-translational modifications, such as glycosylation, which are crucial for proper antibody folding and function, enabling antibodies to better mimic those produced in mammalian systems.
Yeast is an economical and scalable system for large-scale antibody screening, making it a cost-effective choice, especially for working with membrane proteins like GPCRs.
Get in Touch with Our Experts
Ready to take your research to the next level? Our service offers cutting-edge solutions tailored to your needs. Whether you're looking to enhance your antibody discovery process or explore new therapeutic possibilities, our team is here to help. today to learn how we can support your project and drive results with precision.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
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