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Cell-based Target related Yeast Display Library Screening Service

Background Premade Libraries Services Workflow Features Cases

Overview

The discovery of therapeutically relevant antibodies is a cornerstone of modern biomedical research and drug development. Antibodies can be engineered to target specific proteins on the surface of cells, making them invaluable for therapeutic interventions in diseases such as cancer, autoimmune disorders, and infectious diseases. However, identifying antibodies that effectively bind to these cell-based targets can be technically challenging due to the complexity of cellular interactions and the need for high specificity and affinity.

Fig 1. A graph demonstrating antibody targeting cells. (Creative Biolabs Authorized)

Premade Yeast Display Libraries

Species Antibody Library ID Display Technology Library Format Library Size
VHH (Llama) LlaVHH-YDP-1 Yeast Display Naïve VHH 1.5×108
Human HuscL-YDP-3 Yeast Display Naïve scFv 1.9×108

Leveraging Yeast Display Platform for Antibody Discovery Against Cell Targets

By harnessing the biological capabilities of yeast cells to display antibodies on their surface, our yeast display platform offers a robust and scalable method for discovering antibodies that bind specifically to complex cell-based targets. This approach is particularly effective for identifying high-affinity antibodies against cell-surface proteins, as well as antibodies targeting specific cellular states.

Our service provides a systematic, precise, and efficient solution for screening antibodies against a wide range of cell-surface targets (e.g., receptors) and for cell-specific targeting (e.g., specific cell types or differentiated cells). These capabilities ensure the discovery of antibodies with functional relevance for various research and therapeutic applications.

Related Services

We offer a broad spectrum of yeast display library screening services, designed to address diverse research needs. For more details, please explore the services below:

Premade Yeast Display SdAb Library Screening

Premade Yeast Display ScFv Library Screening

Yeast Display Immune Antibody Library Screening

Yeast Display Library Screening for Mutant Epitope Specific Antibody

Yeast Display Library Screening for TCR-Like Antibody

Yeast Display Library Screening for Anti-GPCR Antibody

Yeast Display Library Screening for pH-Dependent Antibody

Workflow

01Custom Antibody Library Generation

Design & construct custom yeast display antibody library

02Screening Against Cell-Based Targets

Cell culture
FACS sorting
Sequencing and delivery

03Characterization of Selected Candidates

Expression and purification
Binding assays
Validation of functional activity

Key Features

Specialized Cell-Based Targeting

Screen antibodies against a wide variety of cell-surface targets (e.g., receptors, ion channels) and cell-specific targets (e.g., immune cells, tumor cells, activated states), ensuring precise targeting for both research and therapeutic applications.

Custom Library Design

Benefit from antibody libraries tailored specifically to your target, enhancing the likelihood of discovering highly effective candidates that meet your project needs.

High Throughput Screening

Efficiently screen vast antibody libraries to quickly identify high-affinity binders. Our yeast display platform couples genotype with phenotype, ensuring functional relevance and suitability for downstream applications.

Cases

Yeast Display Library Screening for Cell-based Target

Fig 2. Case for Yeast Display Library Screening for Cell-based Target. (Creative Biolabs Original)

Our yeast display antibody library screening service equips you with the resources necessary for effective antibody discovery aimed at cell-based targets. Contact us today to discuss how we can help you accelerate your research and therapeutic development efforts.


All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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