Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsTCR-like antibodies are antibodies that bind specifically to peptide-MHC (pMHC) complexes, similar to how T-cell receptors (TCRs) recognize their target antigens. These antibodies hold great promise for immunotherapy, particularly in cancer and infectious diseases, where they can be used to target tumor-associated antigens or pathogens presented on the surface of cells via MHC molecules. The challenge in developing TCR-like antibodies lies in finding specific antibodies that can recognize peptide-MHC complexes with high affinity, as these are often non-immunogenic and structurally challenging to target.
At Creative Biolabs, we recognize the powerful capabilities of yeast display technology for discovering TCR-like antibodies, and we are committed to leveraging these strengths to meet your specific needs. Our experienced scientists work closely with you to design tailored solutions and strategies that align with your unique project goals. Whether you're targeting specific peptide-MHC complexes for cancer immunotherapy, vaccine development, or other applications, we have the expertise to deliver highly specific, high-affinity antibodies. We customize the yeast display platform to optimize antibody discovery, ensuring the selection of functional, therapeutically relevant TCR-like antibodies. From initial consultation to final antibody selection, we are dedicated to providing comprehensive support and innovative solutions that drive your research forward.
| Species | Antibody Library ID | Display Technology | Library Format | Library Size |
| VHH (Llama) | LlaVHH-YDP-1 | Yeast Display | Naïve VHH | 1.5×108 |
| Human | HuscL-YDP-3 | Yeast Display | Naïve scFv | 1.9×108 |
We offer screening services for various antibody types, tackling a wide range of applications and research needs. For further information, please visit the services linked below:
Premade Yeast Display SdAb Library Screening
Premade Yeast Display ScFv Library Screening
Yeast Display Immune Antibody Library Screening
Yeast Display Antibody Library Screening for Cell-based Target
Yeast Display Library Screening for Mutant Epitope Specific Antibody
Yeast Display Library Screening for Anti-GPCR Antibody
Yeast Display Library Screening for pH-Dependent Antibody
Yeast display can present large antibody libraries (up to billions of variants) on the surface of individual yeast cells, allowing for efficient screening against specific peptide-MHC (pMHC) targets. This makes it easier to find antibodies with high specificity and strong binding to pMHC complexes.
Yeast cells can be engineered to display antibodies that are directly screened for binding to peptide-MHC complexes on other yeast or mammalian cells, which increases the physiological relevance of the antibodies being selected.
Whether it's scFvs, Fabs, or VHHs, our platform could accommodate a wide range of formats tailored to specific targets and requirements. This adaptability makes ideal platform for discovering TCR-like antibodies for various applications, from basic research to therapeutic development.
Using flow cytometry, yeast display allows precise sorting of cells that bind specifically to peptide-MHC complexes. This enables quick identification of high-affinity antibodies based on fluorescence signals.
Yeast cells can perform important post-translational modifications (like glycosylation), which are essential for correct antibody folding and function. These modifications ensure that the antibodies not only bind effectively to peptide-MHC complexes but also maintain stability and biological activity.
At Creative Biolabs, we are committed to providing expert solutions that align with your research goals, ensuring the discovery of antibodies with the precision and functionality you require. We invite you to to discuss how our services can support your antibody development needs. Our team is ready to collaborate with you and deliver innovative, tailored solutions to accelerate your progress. We look forward to partnering with you to achieve success in your research and therapeutic endeavors.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
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