Zika Virus Vaccine
Creative Biolabs is a professional vaccine development expert with extensive experience in vaccine design, immunogenicity evaluation, safety evaluation, and production process optimization. We have won good reputation among our worldwide customers for successfully accomplishing numerous challenging projects in viral vaccine development services for Zika virus vaccine. We guarantee the finest results for our customers all over the world.
Zika virus, a member of the Flavivirus family, is spread rapidly through mosquito in South and Central America. Recent studies suggest that Zika virus is related to various diseases, such as microcephaly and congenital Zika syndrome. Microcephaly and congenital Zika syndrome have been causally associated with birth defect during pregnancy. In this condition, Zika virus has been considered as a public health emergency of international concern. Studies show that many groups have tried to develop a safe and effective vaccine to prevent Zika virus infection and severe disease. Up to now, various vaccines have been widely used in Zika virus prevention, including recombinant live attenuated vaccines and DNA vaccines.
Fig.1 The Clinical Trials in Zika Vaccines Development.
The DNA Zika Virus Vaccines
To address the link between Zika virus infection during pregnancy and microcephaly, a DNA virus vaccine has been successfully developed in humans Phase 2 clinical trials. The vaccine is made up of a DNA plasmid encoding the E and PrM proteins, which make up the outer protein coat of the Zika virus virion. The DNA Zika virus vaccine is regarded as a safe and effective tool, which causes only a mild infection characterized by rash, low-grade fever, non-purulent conjunctivitis, to protect recipients from Zika virus infections and diseases.
The Recombinant Live Attenuated Zika Virus Vaccines
The recombinant live attenuated Zika virus vaccines are promising prevention and control methods for infectious disease to elicit T-cell activation and cellular immune responses. Recombinant live attenuated Zika virus vaccines have been attributed to the presence of neutralizing antibodies. The excellent safety, lower side effects of this vaccine in many cases and the compliance with international manufacturing standards lead to the widely used around the world.
Our Services for Zika Virus Vaccines
With a variety of mature and comprehensive platforms and technologies for the evaluation and improvement of vaccine development, we are dedicated to providing the best solutions and protocols customized to ZIKV development.
- Fully integrated viral vaccine services
- Cost-effective vaccine development manner
- Well-established vaccine developing platform
Creative Biolabs is a leader in the field of vaccine development and has focused on the viral vaccine development services for years. We have experienced experts and advanced platforms that are able to provide excellent services. If you are interested in our services, please contact us for more details.
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
