Amine-Doxorubicin Liposome (PEGylated) (CAT#: CLBD014LY)

Description
This formulation is Doxorubicin Liposome (PEGylated) with the amine group, which can react with peptides, antibodies and other NHS-containing biomolecules or nanoparticles. The free carboxyl group on the antibody, peptide or protein can be activated by EDC/sulfo-NHS, and then covalently conjugated to the lipids through displacement of sulfo-NHS groups by amine groups of the liposome.
Lipid Composition
HSPC, Cholesterol, DSPE-PEG(2000), DSPE-PEG(2000)-Amine
Encapsulated Drug
Doxorubicin
Buffer
Ammonium sulfate, pH 7.4
Storage
Store in dark at +4°C and do not freeze
Size
100 nm
Quantity
5mL (available in lyophilized powder)
Molecular Structure
Download
DataSheet MSDS
FAQs Customer Reviews Related Sections
  1. What is the primary function of the amine group on these liposomes?

    The amine group allows covalent conjugation to biomolecules such as peptides or antibodies through reaction with activated carboxyl groups.

  2. What types of biomolecules can these liposomes be conjugated with?

    They can be conjugated with peptides, antibodies, and other NHS-containing biomolecules or nanoparticles.

  3. What advantages do these liposomes have over non-PEGylated versions?

    PEGylated liposomes have improved stability, extended circulation time, and reduced recognition by the immune system.

  4. Why is the daily manufacturing process important for these liposomes?

    It ensures that the liposomes are fresh, stable, and consistent in quality, crucial for experimental reproducibility.

  5. What kind of research fields can benefit from these liposomes?

    Fields such as cancer research, drug delivery, targeted therapy, and immunotherapy can greatly benefit from these liposomes.

  • Reliable Conjugation Efficiency
    We have achieved reliable and efficient conjugation with antibodies using these liposomes, enhancing our targeted therapies.
  • Fast and Efficient Shipping
    Creative Biolabs' fast shipping ensured we received our liposomes in perfect condition and ready for use.
  • Effective Controlled Release
    The controlled release of doxorubicin from these liposomes has improved the therapeutic outcomes in our studies.
  • Enhanced Bioavailability
    We have observed a marked improvement in the bioavailability of doxorubicin when using these liposomes.
  • Excellent Quality Control
    Creative Biolabs' rigorous quality control is evident in the consistent performance of their liposome products.

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For Research Use Only. Not For Clinical Use

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