Anti-ADAMTS14 Aptamer SELEX Service(Cat#: CTApt-1291)

This is an aptamer development services to screening aptamers binds to the ADAMTS14 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ADAMTS14
Alternative Names ADAM Metallopeptidase With Thrombospondin Type 1 Motif 14; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 14; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 14; EC 3.4.24.14; EC 3.4.24.82; EC 3.4.24.- ; ADAM-TS 14; ADAM-TS14; ADAMTS-14; EC 3.4.24; ADAMTS14
Gene ID 140766
UniProt ID Q8WXS8
Target Overview This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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