This is an aptamer development services to screening aptamers binds to the ADAR with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADAR |
| Alternative Names | Adenosine Deaminase RNA Specific; ADAR1; Double-Stranded RNA-Specific Adenosine Deaminase; 136 KDa Double-Stranded RNA-Binding Protein; Interferon-Inducible Protein 4; Interferon-Induced Protein 4; K88DSRBP; DRADA; DSRAD; IFI-4; G1P1; IFI4; P136; Adenosine Deaminase Acting On RNA 1-A; DsRNA Adeonosine Deaminase; DsRNA Adenosine Deaminase; EC 3.5.4.37; EC 3.5.4; AGS6; ADAR; DSH |
| Gene ID | 103 |
| UniProt ID | P55265 |
| Target Overview | This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |