Anti ALPPL-2 Aptamer(Cat#: CTMM-0223-JL16)
This product is an aptamer which binds to the ALPPL-2 with an affinity of <20 nM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
ALPPL-2 |
| Alternative Names |
GCAP; Germ Cell Alkaline Phosphatase; Alkaline Phosphatase, Placental Like 2; Alkaline Phosphatase, Germ Cell Type; Alkaline Phosphatase Nagao Isozyme |
| Gene ID |
251 |
| UniProt ID |
P10696 |
| Target Overview |
ALPPL-2 is ectopically expressed on the cell surface of many pancreatic cancer cell lines and can also be detected in cell secretions, makes this oncofetal protein an attractive target for the serum- and membrane-based diagnosis of pancreatic ductal adenocarcinoma. |
| Chemical Modification |
RNA |
| Length |
60-80 nt |
| Affinity (Kd) |
<20 nM |
| Binding Conditions/Buffer |
4.5 g/L glucose, 5 mmol/L MgCl₂, 0.1 mg/mL yeast tRNA, and 1 mg/mL bovine serum albumin (BSA) in Dulbecco's PBS |
| GC Content |
38 |
| Molecular Weight |
24432.5 |
| Extinction Coefficient |
765800 |
| nmoles/OD260 |
1.091 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
