Anti-BDNF Aptamer(Cat#: CTApt-1730)

This product is an aptamer which binds to BDNF with an affinity of 1-50 nM.

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Summary

Specifications
Target Category Protein
Target BDNF
Alternative Names Brain Derived Neurotrophic Factor; Brain-Derived Neurotrophic Factor; Neurotrophin; Abrineurin; ANON2; BULN2; BDNF
Gene ID 627
UniProt ID P23560
Target Overview This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Type DNA
Length 50-100 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer 2 mM MgCl2 in 1 × PBS, pH 7.2
GC Content 47.56%
Molecular Weight 24887.2 g/mole
nmoles/OD260 1.12
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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