This is an aptamer development services to screening aptamers binds to the BRMS1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BRMS1 |
| Alternative Names | BRMS1 Transcriptional Repressor And Anoikis Regulator; Breast Cancer Metastasis Suppressor; Breast Cancer Metastasis-Suppressor; DKFZP564A063; BRMS1 |
| Gene ID | 25855 |
| UniProt ID | Q9HCU9 |
| Target Overview | This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |