This product is an aptamer which binds to CA15-3 with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | Cancer antigen 15-3 |
| Alternative Names | KL-6; PEM; EMA; ADMCKD1; ADMCKD; MCKD; MCD |
| Gene ID | 4582 |
| UniProt ID | P15941 |
| Target Overview | CA 15-3 is a high molecular weight transmembrane glycoprotein commonly expressed in breast cancer. In addition, primary tumors of the lung and liver may also cause CA 15-3 elevation. |
| Type | DNA |
| Length | <50 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | 100mM NaCl, 20mM Tris-HCl, 2mM MgCl₂, 5mM KCl, 1mM CaCl₂, 0.02% Tween20, pH 7.6 |
| GC Content | 36.00% |
| Molecular Weight | 7707.12 g/mole |
| nmoles/OD260 | 3.82 |