Anti-Carcinoembryonic Antigen Aptamer(Cat#: CTApt-M-1163)

This product is an aptamer which binds to the CEACAM5 with an affinity of <1 nM.

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Summary

Specifications
Target Category Protein
Target CEACAM5
Alternative Names CEA Cell Adhesion Molecule 5; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5; CD66e; CE; Carcinoembryonic Antigen Related Cell Adhesion Molecule 5; Meconium Antigen 100; Carcinoembryonic Antigen; CD66e Antigen
Gene ID 1048
UniProt ID P06731
Target Overview This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Chemical Modification Chimeric
Length 40-60 nt
Affinity (Kd) <1 nM
Binding Conditions/Buffer 30 mM Tris-HCL, 150 mM NaCl, 1.5 mM MgCl2, 2 mM dithiothreitol, 1% bovine serum albumin, pH 7.5.
GC Content 0.4286
Molecular Weight 15869.54 g/mole
Extinction Coefficient 507000 L/(mole·cm)
nmoles/OD260 1.97
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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