Anti-Carcinoembryonic antigen (CEA) Aptamer(Cat#: CTApt-M-007)

This product is an aptamer which binds to the CEA with an affinity of <1 nM.

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5’ Modification
 
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Specifications
Target Category Protein
Target CEA
Alternative Names CEA Cell Adhesion Molecule 5; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5; CD66e; CEA; Carcinoembryonic Antigen Related Cell Adhesion Molecule 5; Meconium Antigen 100; Carcinoembryonic Antigen; CD66e Antigen
Gene ID 1048
UniProt ID P06731
Target Overview This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Chemical Modification DNA
Length 40-60 nt
Affinity (Kd) <1 nM
Binding Conditions/Buffer 30 mM Tris-HCl [pH 7.5], 150 mM NaCl, 1.5 mM MgCl2, 2 mM dithiothreitol, and 1% bovine serum albumin.
GC Content 0.43
Molecular Weight 15007
nmoles/OD260 1.743

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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