Anti-Human 14-3-3 Protein γ Aptamer(Cat#: CTMM-0124-TT4)
This product is an aptamer which binds to the Human 14-3-3 Protein γ with an affinity of 200-1000 pM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
14-3-3 Protein γ |
| Alternative Names |
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma; 14-3-3GAMMA; PPP1R170; Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Gamma Polypeptide; Protein Phosphatase 1, Regulatory Subunit 170; Protein Kinase C Inhibitor Protein 1; 14-3-3 Protein Gamma; KCIP-1; 14-3-3 Gamma; 14-3-3γ; EIEE56; DEE56 |
| Gene ID |
7532 |
| UniProt ID |
P61981 |
| Target Overview |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
100-200 nt |
| Affinity (Kd) |
200-1000 pM |
| Binding Conditions/Buffer |
5 mM Tris-Cl, 150 mM NaCl, pH 7.5 |
| GC Content |
50.88% |
| Molecular Weight |
35358.98 g/mole |
| nmoles/OD260 |
0.94 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
