Anti-PTGDR2 Aptamer SELEX Service(Cat#: CTApt-727)

This is an aptamer development services to screening aptamers binds to the PTGDR2 with an affinity of 1nM~1μM.

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3’ Modification
 
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Summary

Specifications
Target Category Protein
Target PTGDR2
Alternative Names Prostaglandin D2 Receptor 2; CRTH2; Chemoattractant Receptor Homologous Molecule Expressed On T Helper Type 2 Cells; G-Protein Coupled Receptor 44; CD294; GPR44; DL1R; DP2; Chemoattractant Receptor-Homologous Molecule Expressed On TH2 Cells; Chemoattractant Receptor-Homologous Molecule Expressed On Th2 Cells; Putative G-Protein Coupled Receptor 44; G Protein-Coupled Receptor 44; CD294 Antigen; PTGDR2
Gene ID 4502
UniProt ID Q9Y5Y4
Target Overview This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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