Anti-S. Typhimurium Aptamer-CTApt-M-002(Cat#: CTApt-M-002)
This product is an aptamer which binds to the S. Typhimurium OMP with a high affinity.
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Summary
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Specifications
| Target Category |
Protein |
| Target |
S. Typhimurium OMP |
| Target Overview |
The outer membrane proteins (OMPs) of Salmonella have been considered possible candidates for conferring protection against typhoid. OMPs interface the cell with the environment, thus representing important virulence factors with a significant role in the pathobiology of gram-negative bacteria and bacterial adaptation. An OMP of Salmonella enterica serovar Typhimurium with an apparent molecular mass of 49 kDa that is highly immunogenic, evokes humoral and cell-mediated immune responses, and confers 100% protection to immunized rats against challenge with very high doses (up to 100 times the 50% lethal dose) of Salmonella enterica serovar Typhimurium has been identified. |
| Chemical Modification |
DNA |
| Length |
20-40 nt |
| Affinity (Kd) |
N/A |
| Binding Conditions/Buffer |
PBS/1% BSA |
| GC Content |
0.58 |
| Molecular Weight |
12362 |
| nmoles/OD260 |
2.322 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
