This is an aptamer development services to screening aptamers binds to the ACADM with an affinity of 1nM~1μM.
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Target Category | Protein |
Target | ACADM |
Alternative Names | Acyl-CoA Dehydrogenase Medium Chain; MCAD; Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial; Acyl-Coenzyme A Dehydrogenase, C-4 To C-12 Straight Chain; Medium-Chain Acyl-CoA Dehydrogenase; ACAD1; MCADH; Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain; Testicular Tissue Protein Li 7; EC 1.3.99.3; EC 1.3.8.7; EC 1.3.99; ACADM |
Gene ID | 34 |
UniProt ID | P11310 |
Target Overview | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |