This is an aptamer development services to screening aptamers binds to the ADAMTS14 with an affinity of 1nM~1μM.
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Target Category | Protein |
Target | ADAMTS14 |
Alternative Names | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 14; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 14; A Disintegrin And Metalloproteinase With Thrombospondin Motifs 14; EC 3.4.24.14; EC 3.4.24.82; EC 3.4.24.- ; ADAM-TS 14; ADAM-TS14; ADAMTS-14; EC 3.4.24; ADAMTS14 |
Gene ID | 140766 |
UniProt ID | Q8WXS8 |
Target Overview | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |