Anti-ADH5 Aptamer SELEX Service(Cat#: CTApt-690)
This is an aptamer development services to screening aptamers binds to the ADH5 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADH5 |
| Alternative Names |
Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide; ADHX; Glutathione-Dependent Formaldehyde Dehydrogenase; S-(Hydroxymethyl)Glutathione Dehydrogenase; Alcohol Dehydrogenase Class Chi Chain; Alcohol Dehydrogenase Class-III; S-Nitrosoglutathione Reductase; Alcohol Dehydrogenase Class-3; Formaldehyde Dehydrogenase; EC 1.1.1.1; GSH-FDH; ADH-3; FALDH; GSNOR; FDH; Alcohol Dehydrogenase (Class III), Chi Polypeptide; Epididymis Secretory Sperm Binding Protein Li 60p; Alcohol Dehydrogenase 5; EC 1.1.1.284; EC 1.1.1.-; HEL-S-60p; EC 1.1.1; ADH5 |
| Gene ID |
128 |
| UniProt ID |
P11766 |
| Target Overview |
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
