This is an aptamer development services to screening aptamers binds to the ADRA1A with an affinity of 1nM~1μM.
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Target Category | Protein |
Target | ADRA1A |
Alternative Names | Adrenoceptor Alpha 1A; Adrenergic, Alpha-1A-, Receptor; Alpha-1A Adrenergic Receptor; Alpha-1C Adrenergic Receptor; Alpha-1A Adrenoreceptor; Alpha-1A Adrenoceptor; ADRA1L1; ADRA1C; Alpha-Adrenergic Receptor 1c; G Protein Coupled Receptor; ALPHA1AAR; ADRA1A |
Gene ID | 148 |
UniProt ID | P35348 |
Target Overview | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |