Anti-AKR1D1 Aptamer SELEX Service(Cat#: CTApt-1116)

This is an aptamer development services to screening aptamers binds to the AKR1D1 with an affinity of 1nM~1μM.

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5’ Modification
 
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Summary


Specifications
Target Category Protein
Target AKR1D1
Alternative Names Aldo-Keto Reductase Family 1 Member D1; Delta(4)-3-Ketosteroid 5-Beta-Reductase; Delta(4)-3-Oxosteroid 5-Beta-Reductase; SRD5B1; Steroid-5-Beta-Reductase, Beta Polypeptide 1 (3-Oxo-5 Beta-Steroid Delta 4-Dehydrogenase Beta 1) ; Aldo-Keto Reductase Family 1, Member D1 (Delta 4-3-Ketosteroid-5-Beta-Reductase) ; Delta 4-3-Ketosteroid-5-Beta-Reductase; 3-Oxo-5-Beta-Steroid 4-Dehydrogenase; EC 1.3.1.3; 3o5bred; AKR1D1; CBAS2;
Gene ID 6718
UniProt ID P51857
Target Overview The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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