Anti-BACE2 aptamer SELEX Service(Cat#: CTApt-1682)

This is an aptamer development services to screening aptamers binds to the BACE2 with an affinity of 1nM~1μM.

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Summary


Specifications
Target Category Protein
Target BACE2
Alternative Names Beta-Secretase 2; ALP56; DRAP; Membrane-Associated Aspartic Protease 1; Beta-Site APP-Cleaving Enzyme 2; Aspartyl Protease 1; Theta-Secretase; Memapsin-1; AEPLC; ASP21; CEAP1; ASP1; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme 2; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 2; Down Syndrome Region Aspartic Protease; Transmembrane Aspartic Proteinase Asp1; Beta-Site APP Cleaving Enzyme 2; 56 KDa Aspartic-Like Protease; Aspartic-Like Protease 56 KDa; Down Region Aspartic Protease; SLCO3A1/BACE2 Fusion; EC 3.4.23.45; Memapsin 1; EC 3.4.23; CDA13; BACE2; Asp 1; BAE2
Gene ID 25825
UniProt ID Q9Y5Z0
Target Overview This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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