Anti-Human FABP3 Aptamer(Cat#: CTApt-747)

This product is an aptamer which binds to the Human FABP3 with an affinity of 50-200 nM.

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3’ Modification
 
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Summary


Specifications
Target Category Protein
Target FABP3
Alternative Names Fatty Acid Binding Protein 3; H-FABP; Mammary-Derived Growth Inhibitor; O-FABP; FABP11; MDGI; Fatty Acid Binding Protein 3, Muscle And Heart; Heart-Type Fatty Acid-Binding Protein; Fatty Acid-Binding Protein, Heart; Muscle Fatty Acid-Binding Protein; Fatty Acid Binding Protein 11; M-FABP; Fatty Acid Binding Protein 3, Muscle And Heart (Mammary-Derived Growth Inhibitor); Epididymis Secretory Sperm Binding Protein; Fatty Acid-Binding Protein 3
Gene ID 2170
UniProt ID P05413
Target Overview The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
Type DNA
Species Reactivity Human
Affinity (Kd) 50-200 nM
Binding Conditions/Buffer 50 mM NaCl and 2.5 mM MgCl₂
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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