This product is an aptamer which binds to the Human FABP3 with an affinity of 50-200 nM.
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Target Category | Protein |
Target | FABP3 |
Alternative Names | Fatty Acid Binding Protein 3; H-FABP; Mammary-Derived Growth Inhibitor; O-FABP; FABP11; MDGI; Fatty Acid Binding Protein 3, Muscle And Heart; Heart-Type Fatty Acid-Binding Protein; Fatty Acid-Binding Protein, Heart; Muscle Fatty Acid-Binding Protein; Fatty Acid Binding Protein 11; M-FABP; Fatty Acid Binding Protein 3, Muscle And Heart (Mammary-Derived Growth Inhibitor); Epididymis Secretory Sperm Binding Protein; Fatty Acid-Binding Protein 3 |
Gene ID | 2170 |
UniProt ID | P05413 |
Target Overview | The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. |
Type | DNA |
Species Reactivity | Human |
Affinity (Kd) | 50-200 nM |
Binding Conditions/Buffer | 50 mM NaCl and 2.5 mM MgCl₂ |