This product is an ELISA kit for the determination of Human CD55 in the samples of Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Human CD55 as low as 0.09 ng/ml.
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Assay Type | Sandwich ELISA |
Sensitivity | 0.09 ng/ml (0.39-25 ng/ml) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | CD55 |
Cross Reactivity | No significant cross-reactions have been observed between Human CD55 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | 4°C |
Introduction | Complement decay-accelerating factor recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. It acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5, and a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21 during microbial infection. |