This product is an unconjugated anti-Human Complement C4b Monoclonal antibody (CTJS-523) generated from the Mouse. The antibody can be used for WB; ELISA.
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Clonality | Monoclonal |
Clone | CTJS-523 |
Host Animal | Mouse |
Isotype | IgG2b Kappa |
Immunogen | C4B (1347 a.a. - 1446 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEG |
Species Reactivity | Human |
Applications | WB; ELISA |
Application Notes | WB: 1:500 ELISA: 1:100-1:2000 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human complement C4b. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Liquid |
Size | 100 µg |
Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Type | Primary Antibody |
Target Name | C4b |
Alternative Names | Complement C4B (Chido Blood Group); C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 3; Complement Component 4B (Chido Blood Group); Basic Complement C4; Complement Component 4B; Chido Form Of C4; Complement C4B1a; Complement C4-B; CH; C4F; CO4; C4B1; C4B2; C4B3; C4B5; C4BD; C4B12; C4B_2; CPAMD3 |
Gene ID | 721 |
UniProt ID | P0C0L5 |
Introduction | Complement C4b is a protein fragment released from the cleavege of C4. In the activated complement classical pathway or the lectin pathway, C1s and MASP-2 cleave the complement component 4 (C4) alpha chain into C4a and C4b fragments. C4b is an important member of the complement cascade that participates in the formation of the C3 convertases (C4bC2b) and C5 convertases (C4bC2bC3b). |