Rabbit Anti-Human Complement C4A Polyclonal Antibody(Cat#: CTA-307)

Name: Rabbit Anti-Human Complement C4A Polyclonal Antibody
SKU: CTA-307
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement C4A Polyclonal antibody generated from the Rabbit. The antibody can be used for WB; IHC.

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Specifications

Clonality	Polyclonal
Host Animal	Rabbit
Isotype	IgG
Immunogen	Recombinant protein encompassing a sequence within the N-terminus region of human C4. The exact sequence is proprietary.
Species Reactivity	Human
Applications	WB; IHC
Application Notes	WB: 1:500-1:3000 IHC: 1:100-1:1000 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human complement C4A.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100 µL
Storage	Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	C4a
Alternative Names	Complement C4A (Rodgers Blood Group); C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 2; Complement Component 4A (Rodgers Blood Group); Acidic Complement C4; MHC Class III Region Complement; Complement Component 4A; Rodgers Form Of C4; C4A Anaphylatoxin; Complement C4-A; Acidic C4; C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2
Gene ID	720
UniProt ID	P0C0L4

Information

Introduction

Complement C4-A is a protein that in humans is encoded by the C4A gene.This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.