This product is an ELISA kit for the determination of Rabbit Complement Factor B in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Rabbit Complement Factor B as low as 100 pg/mL.
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| Assay Type | Sandwich ELISA |
| Sensitivity | 100 pg/mL (100-2500 pg/mL) |
| Pack Size | 96 tests |
| Species Reactivity | Rabbit |
| Target | Factor B |
| Cross Reactivity | No significant cross-reactions have been observed between Rabbit Complement Factor B and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | 4°C |
| Introduction | Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b. |
Robustness and ease of useExcellentThe kit came with all necessary reagents and detailed documentation. Our lab appreciates the accuracy and consistency it provides in measuring complement Factor B levels. It has significantly streamlined our workflow and improved data quality.
Highly reliableExcellentThe results were both precise and reproducible across multiple assays. The customer service was exceptional, providing prompt responses to my technical queries. This kit has become an essential tool in our lab for studying complement-related pathways.
An excellent addition to our research arsenalExcellentThe calibration curves are consistent, and the assay's sensitivity meets our needs for detecting low concentrations of complement Factor B. It's user-friendly and the data interpretation is straightforward, making it a preferred choice for our experiments.
The quality of the antibodies and reagents is top-notch, ensuring high specificity in our assaysExcellentI highly recommend the ELISA Kit for anyone studying complement components. The ELISA process is well-optimized, and the results are easy to analyze.
The most reliable kits we've used for complement factor analysisExcellentThe detailed protocol included with the kit made the setup straightforward, and we've observed minimal variation between runs. The data quality is excellent, which is critical for our pharmacological studies.