This product is a 25.3kDa recombinant rat MBL2 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.
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| Expressed Host | E.coli |
| Specie Reactivity | Rat |
| Target | MBL2 |
| Molecule Mass | 25.3kDa |
| Purity | >95 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Applications | Positive Control; Immunogen; WB |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Mannose Binding Lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway. Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |
| Alternative Names | Mannose Binding Lectin 2; COLEC1; Mannose-Binding Lectin (Protein C) 2, Soluble (Opsonic Defect); Mannose-Binding Protein C; Collectin-1; MBP-C; MBP1; MBL; Mannose-Binding Lectin 2, Soluble (Opsonic Defect); Mannose-Binding Lectin (Protein C) 2, Soluble; Mannan-Binding Protein; Mannose-Binding Lectin; Mannan-Binding Lectin; HSMBPC; MBL2D; MBPD; MBL2; MBP |
| Gene ID | 64668 |
| UniProt ID | P08661 |