FD-IN-1(Cat#: CTI-009)

This product is a potent factor D antagonist, it inhibits factor D with the IC50 of 12 nM. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively.

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Specifications
CAS No. 1646682-14-5
Formula C₂₃H₂₃NO₄
Molecular Weight 377.43
SMILES O=C(O)CC1=CC=CC=C1OCC2=CC=CC(C3=CC([C@H](N)CO)=CC=C3)=C2
IC50 IC50: 12 nM
Purity 95%
Solubility Soluble in DMSO
Storage Store at -4°C for short term; at -20 °C for long-term storage.
Target Factor D
Introduction The Factor D is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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