This product is a conjugated anti-Human Complement C4BPA Monoclonal antibody (CTJS-112) generated from the Mouse. The antibody can be used for IF, IHC, FC.
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| Clonality | Monoclonal |
| Clone | CTJS-112 |
| Host Animal | Mouse |
| Isotype | IgG1 κ |
| Immunogen | Recombinant human C4BPA, a.a. 294-491 |
| Species Reactivity | Human |
| Applications | IF; IHC; FC |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement C4BPA. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | PE |
| Format | Liquid |
| Size | 200 µg |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | C4BPA |
| Alternative Names | Complement Component 4 Binding Protein Alpha; C4b-Binding Protein Alpha Chain ; Proline-Rich Protein; C4BP; Complement Component 4-Binding Protein, Alpha; C4BPA; C4bp |
| Gene ID | 722 |
| UniProt ID | P04003 |
| Introduction | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |