This product is an unconjugated anti-Human Complement C2b Monoclonal antibody (CTJS-718) generated from the Mouse. The antibody can be used for WB; IP.
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| Clonality | Monoclonal |
| Clone | CTJS-718 |
| Host Animal | Mouse |
| Isotype | IgG2a |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Complement Component C2 Ala21-Leu752 |
| Species Reactivity | Human |
| Applications | WB; IP |
| Application Notes | WB: 1 µg/mL IP: 25 µg/mL The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human C2b. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Lyophilized |
| Size | 25; 100 µg |
| Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Type | Primary Antibody |
| Target Name | C2b |
| Alternative Names | Complement C2b; C2b fragment |
| Gene ID | 717 |
| UniProt ID | P06681 |
| Introduction | Complement C2 in the complement classical pathway and complement lectin pathway is cleaved into the large C2a and the small C2b fragment by C1s or MASP2, respectively. C2b binds to C4b forming C4bC2b complex, namely C3 convertase. |