Mouse Anti-Human Complement Factor Bb Monoclonal Antibody (CTJS-602)(Cat#: CTA-129)

This product is an unconjugated anti-Human Complement Factor Bb Monoclonal antibody (CTJS-602) generated from the Mouse. The antibody can be used for WB; ELISA.

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Specifications
Clonality Monoclonal
Clone CTJS-602
Host Animal Mouse
Isotype IgG1κ
Immunogen Complement factor B purified from human plasma and adsorbed to aluminum hydroxide gel
Species Reactivity Human
Applications WB; ELISA
Application Notes WB: 1:100-1:2000
ELISA: 1:100-1:2000
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with the Bb fragment of human factor B.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 25; 100 µL
Storage Store at 4°C. Do not freeze.
Type Primary Antibody
Target
Target Name Factor Bb
Alternative Names Complement Factor Bb; Complement Factor Bb fragment; Factor Bb fragment; CF Bb
Gene ID 629
UniProt ID P00751
Information
Introduction Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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