Rabbit Anti-Human Factor B Bb Polyclonal Antibody(Cat#: CTA-602)

Name: Rabbit Anti-Human Factor B Bb Polyclonal Antibody
SKU: CTA-602
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement Factor B Bb Polyclonal antibody generated from the Rabbit. The antibody can be used for EIA, RIA.

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Specifications

Clonality	Polyclonal
Host Animal	Rabbit
Isotype	IgG
Epitope	C-terminal Host species
Immunogen	Recombiannt Human complement factor B-Bb expressed in E. Coli., a.a. 260-764
Species Reactivity	Human
Applications	EIA; RIA
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Complement Factor B Bb.
Purity	≥95% as determined by SDS-PAGE
Conjugation	Unconjugated
Format	Liquid
Size	150 ug
Storage	Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle.
Type	Primary Antibody

Target

Target Name	Factor Bb
Alternative Names	Complement Factor Bb; Complement Factor Bb fragment; Factor Bb fragment; CF Bb
Gene ID	629
UniProt ID	P00751

Information

Introduction

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.