Mouse Anti-Human Factor B Bb Monoclonal Antibody (CTJS-668) [iFluor® 546](Cat#: CTA-596)

Name: Mouse Anti-Human Factor B Bb Monoclonal Antibody (CTJS-668) [iFluor® 546]
SKU: CTA-596
Rating: 5 (1 reviews)

This product is a conjugated anti-Human Complement Factor B Bb Monoclonal antibody (CTJS-668) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.

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Specifications

Clonality	Monoclonal
Clone	CTJS-668
Host Animal	Mouse
Isotype	IgG1 κ
Immunogen	Recombinant Human complement factor B, a.a. 426-520
Species Reactivity	Human
Applications	WB; IF; IHC; FC
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Complement Factor B Bb.
Purity	≥95% as determined by SDS-PAGE
Conjugation	iFluor® 546
Format	Liquid
Size	200 µg
Storage	Store in dark at 4°C. Do Not Freeze.
Type	Primary Antibody

Target

Target Name	Factor Bb
Alternative Names	Complement Factor Bb; Complement Factor Bb fragment; Factor Bb fragment; CF Bb
Gene ID	629
UniProt ID	P00751

Information

Introduction

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.