This product is a 205 kDa native human C4 protein isolated from normal human serum. It is availible for Functional Assays.
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Specie Reactivity | Human |
Target | C4 |
Molecule Mass | 205 kDa |
Purity | >90 % determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
Applications | Functional Assays |
Product Form | Frozen liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Complement C4 is a non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. It plays important roles in immunity, tolerance, and autoimmunity with the other numerous components. Furthermore, it is a crucial factor in connecting the recognition pathways of the overall system instigated by antibody-antigen (Ab-Ag) complexes to the other effector proteins of the innate immune response. |
Alternative Names | Complement C4; Complement Component C4; Complement Component 4 ; C4 |
The purity and activity of the protein are outstandingExcellentWe've used it in both in vitro settings with consistently reliable results. Additionally, the product's stability during storage has been impressive, making it a great value for the price.
It has consistently delivered high-quality resultsExcellentThe protein's activity is well-preserved. The supplier provides a comprehensive data sheet, which is very helpful for ensuring we use the product correctly in our experiments. Highly recommend it for complement-related studies.
IndispensableExcellentIts high purity ensures that our experimental outcomes are not compromised by contaminants. The product is easy to reconstitute and integrates well into our assays. Shipping was prompt, and the customer service has been responsive to any queries we've had.
Using reliable reagents is crucial for our workExcellentThis C4 protein has exceeded expectations in terms of consistency and performance. We've used it in several ELISA assays, and the results have been both reproducible and accurate. The protein's activity remained stable across multiple experiments, which speaks to its quality.
Our go-to reagent for studies on complement activationExcellentThe protein arrived in excellent condition, and the accompanying documentation was very thorough. We appreciate the fact that the protein is free from any significant degradation, allowing us to trust the results of our assays. It has become a staple in our lab.