This product is an ELISA kit for the determination of Complement C4 in rat Serum, plasma and other biological fluids. It is highly sensitive and available for the detection of Rat Complement C4 as low as 2.74 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Assay Type | Sandwich ELISA |
Sensitivity | 2.74 ng/mL (6.25-400 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Rat |
Target | C4 |
Cross Reactivity | No significant cross-reactions have been observed between Rat Complement C4 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | The storage of components varies. Please refer to the instructions for details. |
Introduction | Complement C4 is a major histocompatibility complex class-III protein. It is non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. |